Interests

I work at VUIIS in the Cellular and Molecular Imaging research area.

Projects

I design and engineer novel report system for apoptosis drug screening.  I also develop aptamers or peptides against tumor markers and application of aptamers or peptides in guide imaging probe(s) in the application of monitoring tumor genesis and valuating therapeutic effectiveness.  

Publications

Nickels, M., J. Xie, J Cobb, J. Gore, W.Pham. Functionalization of iron oxide nanoparticles with a versatile epoxy amine linker. J. Mater. Chem., 20, 4776â?°Ã?Ã?4780 (2010).

Xie. J., Crooke, P., Soltman, J., Brandt, R.S., McKinney, B., and Brandt, S.JA Computational Model of Quantitative Chromatin Immunoprecipitation (ChIP) Analysis. Cancer Inform. 4:137-145 (2008).

Xie, J.., K. Shultz, L. Flye, F. Jiang, D. Head, R. Briggs. Overexpression of GSTA2 protects against cell cycle arrest and apoptosis induced by the DNA inter-strand crosslinking nitrogen mustard, mechlorethamine. J. Cell. Biochem.  95(2):339-351 (2005).

Xie, J.,  Cai, T.,  Zhang, H., Lan, M. S. and Notkins,  A. L. The Zinc-Finger Transcription Factor IA-1 is Expressed During Embryo Development and Interacts with the Cbl-Associated Protein, CAP. Genomics. 80:54-61 (2002).

Xie, J., Briggs, J. A., Briggs, R.C. Human Myeloid Nuclear Antigen MNDA Interacts with YY1 and Stimulates DNA Binding. J. Cell Biochem. 70, 489-506 (1998).