I am interested in using optical techniques for the diagnosis of pathologies. Specifically I use fluorescence and Raman spectroscopy to detect precancer and cancer tissues.
Currently I have projects using Raman spectroscopy to detect breast cancer, to help identify pre-term labor changes in the cervix, and skin cancer detection. Part of the skin cancer project is developing a hand-held device for tissue differentiation in the dermatology clinic for quick and accurate diagnosis.
X. Bi, B. Rexer, C. L. Arteaga, M. Guo, M. Li, A. Mahadevan-Jansen, Determination of HER2 amplification status in breast cancer cells using Raman spectroscopy, 2010, Proc. SPIE, Vol. 7560, 7560-30 (2010).
Kanter EM, Vargis E, Majumder S, Keller MD, Beaven RB, Rao GG, A Mahadevan-Jansen. Application of Raman Spectroscopy for Cervical Dysplasia Diagnosis. Journal of Biophotonics, 2: (1-2), 81-90, 2009.
X. Bi, CA Patil, C. Morrissey, M. P. Roudier, A. Mahadevan-Jansen, JS Nyman, Characterization of bone quality in prostate cancer bone metastases using Raman spectroscopy, 2010, Proc. SPIE, Vol. 7458, 7458F-183 (2010)
C.A. Patil, H. Krishnamoorthi, D.L. Ellis, T.G. van Leeuwen, and A. Mahadevan-Jansen. A Clinical Probe for Combined Raman spectroscopy - optical coherence tomography for evaluation of skin cancers. Paper 7548A-20 presented at SPIE Photonics West, San Francisco, California, January 23-28, 2010.